Date Published

November 18, 2025

Updated For

ALS PCS Version ALS PCS Version 5.2

Question:

Should Midazolam be considered in the management of a trauma patient with trismus? In the absence of tonic/clonic seizure. 

Answer:

Although trismus in trauma may be due to pain which midazolam may assist with, it may also be due to mechanical obstruction or traumatic brain injury. Midazolam is unlikely to break the trismus and could be detrimental The risk of giving midazolam would be hypotension, bradycardia and apnea. If the patient has trismus and you inadvertently cause apnea, you may not be able to support ventilations. In addition, bradycardia and hypotension can also be lethal. SWORBHP Medical Council suggests expedient transport and managing the airway with nasal trumpets/BVM in these rare situations. 

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