Trends in auditing have shown that salbutamol is not being administered when indicated (without documented rationale). Let’s explore the potential benefits of salbutamol for bronchoconstriction…

Mechanism of Action ​

Salbutamol is a Beta-2 adrenergic receptor agonist. It works in two main ways:​

1) relaxes the bronchial smooth muscle​

2) Inhibits the release of hypersensitivity mediators (mast cells) to reduce secretions

Assessment of the Patient with Bronchoconstriction

• Assess ABC’s​
  • Airway – Patency ​
  • Breathing – Quality, Rate, and Rhythm​
  • Circulation – Signs of perfusion ​
• Full set of Vital Signs (consider ETCO2 waveform!)​
• Auscultate lung sounds​​

Signs and Symptoms of Bronchoconstriction:​

• Wheezing​
• Dyspnea​
• Coughing ​
• Chest tightness/pain​
• Anxiety (sensation caused by Hypoxia)

Potential Benefits​

Salbutamol can do the following for patients experiencing bronchoconstriction:​

• Decrease shortness of breath​
• Decrease respiratory rate​
• Decrease patient anxiety​
• Increase SpO2​
• Improve work of breathing

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