Date Published

February 11, 2020

Updated For

ALS PCS Version


Did you know... patients in cardiac arrest should NOT routinely be considered for naloxone administration.

Naloxone can reverse respiratory depression and apnea in opioid toxicity but it does NOT reverse cardiac arrest. Focus during cardiac arrest should be on effective CPR and ventilation in addition to defibrillation and epinephrine (ACPs). If you are considering opioid toxicity as the cause for arrest AND you have all other aspects of high quality resuscitation underway, with the ability to administer naloxone without detracting from this resuscitation, it can be considered.


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