When giving Epinephrine for anaphylaxis is it expectable to delay administration of diphenhydramine following the first dose of Epinephrine if it is getting close to the 5 minute dose interval for the second dose of Epinephrine and the patient is requiring the second dose of Epinephrine? My understanding is that Epinephrine in anaphylaxis is the priority medication and I could use clarification as to whether or not it is okay to delay administration of diphenhydramine until after the second dose of Epinephrine if the patient requires a second dose and we were not able to administer diphenhydramine in between the required 5 minute dose interval for the second dose of Epinephrine. 

If you have already administered epinephrine, it is reasonable to give diphenhydramine any time thereafter. We understand that calls are dynamic and some situations may allow for the administration of diphenhydramine prior to a potential need for a second dose of epinephrine and some may not. In true anaphylaxis, epinephrine is the treatment priority as it has numerous therapeutic properties and is one of the few “silver bullets” of medicine.  

BLS,BLS-FTTS,Cardiac/Circulation,Trauma Cardiac Arrest,Trauma Patient

Blunt Trauma, Field Trauma Triage Standard, FTTS, Local Trauma Hospital, LTH, Penetrating Trauma, Signs of Life, trauma TOR, Traumatic Cardiac Arrest

No additional resources available for this #SWORBHPTip.